Unmet Need

The World Health Organisation defines hepatitis B as “a potentially life-threatening liver infection caused by the hepatitis B virus (HBV). It is a major global health problem. It can cause chronic infection and puts people at high risk of death from cirrhosis and liver cancer.”

  • Approx. 2 billion people are infected with HBV and ~250 million living with chronic hepatitis B (CHB) virus infection

  • Viral hepatitis is the 7th ranked cause of human death
  • 15-25% of people with CHB develop advanced liver disease &/or HCC (without appropriate clinical management)

  • Liver cancer is the 3rd most common cause of cancer death globally