ClearB is working to develop therapeutic vaccines designed to redirect patients’ immune systems toward functional cure of hepatitis B.

The World Health Organisation defines hepatitis B as “a potentially life-threatening liver infection caused by the hepatitis B virus (HBV). It is a major global health problem. It can cause chronic infection and puts people at high risk of death from cirrhosis and liver cancer.

At ClearB, we are working to develop immunotherapies which harness the bodies’ natural immune system to result in a functional cure for chronic hepatitis B (CHB).

  • Approx. 2 billion people are infected with HBV and ~250 million living with chronic hepatitis B (CHB) virus infection

  • Viral hepatitis is the 7th ranked cause of human death
  • 15-25% of people with CHB develop advanced liver disease &/or HCC (without appropriate clinical management)

  • Liver cancer is the 3rd most common cause of cancer death globally